Chloride transporters and GABA polarity in developmental, neurological and psychiatric conditions

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Cerebrospinal fluid GABA levels in various neurological and psychiatric diseases.

Cerebrospinal fluid gamma-aminobutyric acid (CSF-GABA) was analysed by radioreceptor assay in 16 normal controls and 84 patients with various neurological and psychiatric diseases. In patients with spinocerebellar degeneration, neuro-Behçet's syndrome and Parkinson's disease, CSF-GABA levels were decreased. On the other hand, increased CSF-GABA levels were detected in patients with meningitis.

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Cerebrospinal fluid gamma-aminobutyric acid (CSF-GABA) was analysed by radioreceptor assay in 16 normal controls and 84 patients with various neurological and psychiatric diseases. In patients with spinocerebellar degeneration, neuro-Beh9et's syndrome and Parkinson's disease, CSF-GABA levels were decreased. On the other hand, increased CSF-GABA levels were detected in patients with meningitis.

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ژورنال

عنوان ژورنال: Neuroscience & Biobehavioral Reviews

سال: 2018

ISSN: 0149-7634

DOI: 10.1016/j.neubiorev.2018.05.001